Protein Details: Potassium channel subfamily K member 17

Protein ID

ICDB_Pro_1412

Protein Name

Potassium channel subfamily K member 17

Gene Name

KCNK17; TALK2; TASK4; UNQ5816/PRO19634

Organism

Homo sapiens (Human)

Length

332 amino acids

AlphaFoldDB

AF-Q96T54-F1-model_v4.pdb

Function

Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.

Sequence

MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPDREPESHSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Heart Conduction Disease and Cardiac Conduction Defect

Location

DOI ID

10.1006/bbrc.2001.4562; 10.1016/s0014-5793(01)02222-0; 10.1101/gr.1293003; 10.1038/nature02055; 10.1101/gr.2596504

RefSeq

NP_001128583.1 [Q96T54-4]; NP_113648.2 [Q96T54-3]